Research
May 20, 2024

Far UV-C Light at 222 nm Destroys Biofilms Formed by Periodontitis Pathogens

Recent research published in the Journal of Microbiology, Immunology and Infection evaluates the efficacy of Far UV-C light at 222 nm in destroying biofilms formed by periodontitis pathogens. The study, conducted by a team from Yamaguchi University, demonstrates that this specific wavelength effectively disrupts and sterilizes biofilms created by Fusobacterium nucleatum, Porphyromonas gingivalis, and Streptococcus mutans. Using confocal laser microscopy and scanning electron microscopy, the researchers observed significant reductions in biofilm thickness and structural integrity post-irradiation, showcasing the potential of Far UV-C light as a non-invasive treatment option.

The study highlights the advantages of Far UV-C light over traditional deep ultraviolet (D-UV) light, noting that it causes less DNA damage and is less cytotoxic. Additionally, a newly developed thin fiber-type Far UV-C irradiator was tested for safety and effectiveness in reducing bacterial counts in rodent models, confirming its potential applicability in clinical settings. These findings open new avenues for improving periodontal disease management, particularly in cases resistant to conventional antimicrobial treatments. Read the full study here.

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